Following his contributions to Ghana's independence struggles, JB Danquah was arrested and detained under the Preventive Detention Act on the grounds of involvement with alleged plans to overthrow the CPP government on October 3, 1961.

He was, however, released on June 22, 1962.

After his release, two years along the line, JB Danquah was again arrested on January 8, 1964, for allegedly plotting against President .  While in prison, the former member of the United Gold Coast Convention (UGCC) wrote a letter to , calling for his release based on health grounds.

In a video shared on YouTube by Nana Kollynx, it contained the detailed letter from JB Danquah to before his demise.