Formerly known as Cantonments Road, the stretch is also widely recognized for its bustling nightlife, serving as a hub for popular bars, clubs, and restaurants such as Papaye, Frankies, Kona Grill and Lounge, among others.

Aside from the popular Oxford Street, notable landmarks in the Osu area include the Black Star Square, Kwame Nkrumah Mausoleum, Osu Castle, Asomdwee Park, and Cantonments.

However, this only represents part of the story.

The Chief Priest of Osu Nadu/Klottey, Wor-Lumor Nuumo Noi Sekanku Kpenuku II, made surprising revelations about additional areas in Accra that fall under Osu during GhanaWeb's People and Places programme.