
WHO restricts Ervebo use in Bundibugyo outbreak
The World Health Organisation (WHO) has issued new emergency guidance on using the licensed Ervebo vaccine during outbreaks of Bundibugyo virus disease, now limiting its use to research protocols.
It recommended developing and sharing master protocols for ring vaccination trials and high-quality observational studies to ensure timely, coordinated evidence generation during the outbreak and future emergency responses in affected countries.
According to the organisation, a ring vaccination randomised controlled trial would be the most robust approach for determining Ervebo’s efficacy against Bundibugyo virus disease among affected populations.
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