The protesters, organised by the Democracy Hub group, were calling on the government to take decisive action against galamsey operators, whose activities have severely degraded forests, contaminated water bodies, and displaced communities.
The protesters aimed to shine a light on what they termed a "lack of political will" to combat the illegal mining menace, despite public declarations of government efforts to halt it.
Speaking on the arrest and injustice meted out to to the protestors, Prof Opoku-Agyemang described the protesters as innocent citizens exercising their democratic rights and called on the government to swiftly release those in custody.
During her campaign tour in Bogoso in the Western Region, Prof Opoku-Agyemang expressed her displeasure at the treatment of the 42 young protesters who were detained by the police at the 37 lorry station near the Revolutionary Square.