Ghana forward Ernest Nuamah was at the double for Lyon as they booked a last eight Europa League tie against Manchester United.
Lyon were on the front foot from the onset and were rewarded with a Georges Mikautadze finish after 14 minutes.
Mikautadze then turned provider eight minutes before the break for Nuamah, who tucked home from close range.
The Mikautadze and Nuamah show continued after the break.