The deceased, John Scott Hughes, is reported to have invited Ms Agbomadzi to meet him at American House in East Legon.
They then proceeded to Philipo's Movie House, a local spot in the area, where he rented a room for the two of them.
According to the prosecution, the pair, described as "girlfriend" and "boyfriend," watched pornographic content together and later engaged in consensual sexual activity.
During the encounter, Hughes allegedly lost consciousness and collapsed on the floor, prompting Ms Agbomadzi to rush to the reception area for help.